20 curated peptide combinations organized by goal. Each stack shows synergistic peptides, sample protocols, and usage notes.
Maximize GH pulses for muscle gain and recovery
Sample Protocol CJC-1295: 100–200 mcg nightly SC. Ipamorelin: 200–300 mcg 2–3x/day SC. IGF-1 LR3: 20–50 mcg post-workout SC. Cycle: 8–12 weeks.
Notes Safest beginner GH stack. Add carbs post-IGF-1 LR3 to avoid hypoglycemia. Take GH peptides on empty stomach.
Aggressive GH release and myostatin inhibition
Sample Protocol Hexarelin: 100–300 mcg 2–3x/day SC. GHRP-2: 100–300 mcg 2–3x/day SC. Follistatin-344: 100–200 mcg daily SC (short 10–14 day cycles). Cycle: 8–12 weeks for GH peptides.
Notes High potency — for advanced users only. Monitor prolactin and cortisol levels. Follistatin cycles must be kept short.
Localized hypertrophy and tissue repair
Sample Protocol PEG-MGF: 200–400 mcg 2–3x/week IM (post-workout into trained muscles). TB-500: 2–7.5 mg 2x/week SC. Sermorelin: 300–500 mcg nightly SC. Cycle: 4–8 weeks.
Notes Ideal for athletes. Inject PEG-MGF bilaterally into worked muscles for localized effect.
Muscle preservation during fat loss
Sample Protocol CJC-1295: 100–200 mcg nightly SC. Ipamorelin: 200–300 mcg 2–3x/day SC. AOD 9604: 300–500 mcg daily SC (morning). Cycle: 8–12 weeks.
Notes Balances anabolism with fat burn. Pair with structured training and moderate caloric deficit.
Aggressive weight loss with muscle sparing
Sample Protocol Semaglutide: 0.25–2.4 mg weekly SC (titrate over 4–8 weeks). AOD 9604: 300–500 mcg daily SC. Continuous with titration. Consider BPC-157 oral for gut protection.
Notes GI side effects common during titration — start low. Use BPC-157 oral if experiencing nausea. Physician supervision essential.
Visceral fat targeting + metabolic boost
Sample Protocol Tesamorelin: 1–2 mg nightly SC. AOD 9604: 300–500 mcg daily SC. MOTS-c: 5–10 mg 3x/week SC. Cycle: 8–12 weeks.
Notes Tesamorelin is FDA-approved for HIV lipodystrophy. Great stack for older users concerned about metabolic health. Monitor IGF-1 levels.
Daily fat loss with hormonal balance
Sample Protocol Liraglutide: 0.6–3 mg daily SC (titrate). GHRP-6: 100–300 mcg 2–3x/day SC. Kisspeptin-10: 100–200 mcg weekly SC. Continuous for GLP-1.
Notes GHRP-6 increases hunger — countered by liraglutide appetite suppression. Monitor hormone panels.
Next-gen fat loss with GH preservation
Sample Protocol Retatrutide: 4–12 mg weekly SC (titrate slowly). Ipamorelin: 200–300 mcg 2–3x/day SC. Follow trial protocols.
Notes Retatrutide is pending FDA approval (Phase 3 trials 2026). Muscle-friendly stack. Titrate slowly to manage GI effects.
Comprehensive tissue, gut, and inflammation repair
Sample Protocol BPC-157: 250–500 mcg/day SC (near injury) or oral for gut. TB-500: 2–7.5 mg 2x/week SC (loading), then 2–5 mg/week. KPV: 200–500 mcg daily oral/SC. Cycle: 4–6 weeks.
Notes Gold standard recovery stack for athletes. Inject BPC-157 near injury site for best results. Use oral KPV for gut inflammation.
Neuropathy treatment and wound healing
Sample Protocol ARA-290: 2–4 mg daily SC (28-day cycle). BPC-157: 250–500 mcg/day SC. LL-37: 100–200 mcg daily topical/SC. Short cycles.
Notes Best for chronic pain and diabetic neuropathy. LL-37 provides antimicrobial bonus for wound care.
Post-injury immune boost with restorative sleep
Sample Protocol Thymosin Alpha-1: 1.6 mg 2x/week SC. TB-500: 2–7.5 mg 2x/week SC. DSIP: 100–300 mcg nightly SC (5–10 day blocks). Cycle: 4–8 weeks.
Notes Excellent post-surgery stack. DSIP aids rest which is critical for healing. Monitor immune markers.
Telomere extension + skin and metabolic support
Sample Protocol Epitalon: 5–10 mg daily SC/nasal for 10–20 days (2–3 cycles/year). GHK-Cu: 1–2 mg daily SC or 0.1–1% cream daily. MOTS-c: 5–10 mg 3x/week SC (4–8 week cycles).
Notes Russian-inspired longevity protocol. GHK-Cu topical can be used continuously. Pair with a comprehensive skincare routine.
Energy restoration and oxidative stress reduction
Sample Protocol SS-31: 5–10 mg daily SC (4–12 weeks). MOTS-c: 5–10 mg 3x/week SC. Epitalon: 5–10 mg daily for 10–20 day bursts.
Notes For age-related energy decline and fatigue. Monitor energy levels and adjust. SS-31 is in Phase 3 trials for mitochondrial conditions.
Anti-aging skin with hormonal balance
Sample Protocol GHK-Cu: 1–2 mg daily SC or topical cream. Melanotan I: 0.25–1 mg daily SC (loading 5–10 days), then 0.25–0.5 mg 1–2x/week. Kisspeptin-10: 100–200 mcg weekly SC.
Notes UV protection bonus from Melanotan I. Avoid over-tanning — monitor mole changes. GHK-Cu topical can be continuous.
Maximum memory, focus, and brain repair
Sample Protocol Semax: 300–600 mcg nasal daily (split 2–3x). Dihexa: 5–10 mg oral daily. Pinealon: 1–2 mg daily SC/sublingual for 10–20 days. Cycle: 4–8 weeks.
Notes Potent nootropic stack — start low with each compound. Best for high performers and demanding cognitive work.
Stress reduction with restorative sleep
Sample Protocol Selank: 300–900 mcg nasal daily (split doses). DSIP: 100–300 mcg SC before bed (5–10 day blocks). Semax: 300–600 mcg nasal in morning. Cycle: 10–20 days on, 10 off.
Notes Russian nootropic combination. Non-addictive and well-tolerated. Semax in morning, Selank throughout day, DSIP before bed.
Brain health, repair, and long-term protection
Sample Protocol ARA-290: 2–4 mg daily SC (28-day cycles). SS-31: 5–10 mg daily SC. Dihexa: 5–10 mg oral daily. Short 28-day cycles.
Notes For cognitive longevity and neuroprotection. Research-focused stack. Monitor for overstimulation with Dihexa.
Comprehensive libido and sexual function boost
Sample Protocol PT-141: 1–2 mg SC as needed (2–4 hours before). Kisspeptin-10: 100–200 mcg weekly SC. Melanotan II: 0.25–1 mg daily SC (loading), then maintenance. On-demand use.
Notes PT-141 is FDA-approved (Vyleesi) for women. On-demand dosing — limit PT-141 to 2–3x/week. Watch for nausea.
Anti-aging skin with sunless tanning
Sample Protocol GHK-Cu: topical cream daily or 1–2 mg SC. Melanotan I: 0.25–1 mg daily SC (loading). Melanotan II: 0.25–0.5 mg 1–2x/week (maintenance). Cycle tanning phases.
Notes Sunless protection approach. Use GHK-Cu topical daily for continuous skin benefits. Monitor moles for changes.
Comprehensive immune defense and inflammation control
Sample Protocol Thymosin Alpha-1: 1.6 mg 2x/week SC. LL-37: 100–200 mcg daily topical/SC. KPV: 200–500 mcg daily oral/SC. Short-term cycles.
Notes Great for seasonal immune boosts or post-illness recovery. Short-term use recommended. Monitor immune markers.
Important
Stacking increases complexity and potential interactions. Always consult a licensed physician, monitor bloodwork (IGF-1, hormones, liver/kidney panels), and use pharmaceutical-grade sources. Start low, titrate up, and cycle appropriately. Many peptides are WADA-banned for competitive athletes.
Begin with 1–2 peptides before adding more. Assess tolerance and effects individually before stacking.
GH peptides work best on an empty stomach before bed. Healing peptides can be taken anytime. Nootropics are best in the morning.
Follow recommended cycle lengths. Most peptides need 4–12 weeks on with off periods to prevent receptor desensitization.
Track bloodwork, sleep quality, and subjective effects. Adjust doses based on response. Work with a knowledgeable physician.
Be cautious combining peptides that act on the same receptors (e.g., multiple GH secretagogues). Overlap can amplify side effects without proportional benefit.
Only use pharmaceutical-grade peptides from third-party tested suppliers with Certificates of Analysis. Quality directly impacts safety and efficacy.