LL-37
Antimicrobial peptide.
Mechanism of Action
Disrupts bacterial membranes.
Key Benefits
- Antimicrobial
- Wound healing
Common Uses
What to Expect
Onset
Antimicrobial effects begin within days; wound healing improvements within 3–5 days
Duration
Used short-term until infection resolves or wound heals; not a long-cycle peptide
What Users Report
- Faster resolution of localized infections — wounds that were slow to heal begin closing
- Improved wound healing when applied topically to stubborn or slow-healing injuries
- Sometimes a mild inflammatory response initially as the immune system activates against pathogens
- Best used for targeted purposes (specific infections or wounds) rather than general daily wellness
- Can cause mild irritation at the injection or application site
- Biofilm disruption — some users report improvement in chronic infections that resisted other treatments
- Most effective as part of a targeted antimicrobial strategy, not as a standalone
Typical Timeline
Days 1–2: Immune activation begins; possible mild local inflammation. Days 3–5: Antimicrobial effects become apparent; wound healing accelerates. Days 5–10: Significant improvement in infection or wound status. As needed: Continue until resolution; typically short-duration use.
Side Effects
- Possible irritation
Dosage Protocol
100–200 mcg topically or subcutaneously daily. Cycles: As needed for infection; short-term.
Always consult a physician before starting any peptide protocol.
Administration
Topical or injection
FDA Status
Category 2 (potential reclassification 2026)