SS-31
Elamipretide, MTP-131
Mitochondria-penetrating peptide that reduces oxidative damage.
Mechanism of Action
Localizes to inner mitochondrial membrane, scavenges ROS, and improves ATP production.
Key Benefits
- Boosts cellular energy
- Reduces fatigue
- Organ protection
Common Uses
What to Expect
Onset
Energy improvements within days to 1–2 weeks; more noticeable in those with mitochondrial dysfunction
Duration
Effects build over 4–12 week cycles; cellular repair benefits persist after stopping
What Users Report
- Increased cellular energy and noticeably reduced fatigue — described as 'batteries being recharged'
- Improved physical stamina and exercise endurance
- A subtle but clear improvement in overall vitality — feeling more 'alive' and functional
- Enhanced exercise tolerance — able to push harder and recover faster
- Effects are most dramatic in those with existing mitochondrial dysfunction or age-related fatigue
- Some describe it as reversing the feeling of 'running on empty' that comes with aging
- Mild injection site reactions are the main side effect; generally well tolerated
Typical Timeline
Days 1–7: Subtle energy improvements begin. Weeks 1–2: Fatigue reduction becomes noticeable; exercise feels easier. Weeks 2–6: Stamina and endurance measurably improve. Weeks 6–12: Full cycle benefits; significant improvement in mitochondrial function markers. Post-cycle: Cellular repair benefits persist as mitochondrial health has been restored.
Side Effects
- Mild injection site reactions
Dosage Protocol
Research/wellness protocols: 5–10 mg daily subcutaneous (up to 40 mg in clinical trials for specific diseases). Cycle 4–12 weeks with monitoring. Research use only.
Always consult a physician before starting any peptide protocol.
Administration
Subcutaneous injection
FDA Status
Investigational (Phase 3 for mitochondrial/heart conditions)
Stacks Well With
- MOTS-c
- Epitalon
Tags
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