Melanotan II
Melanocortin agonist for tanning and libido.
Mechanism of Action
Stimulates melanocytes and MC4R.
Key Benefits
- Tanning without sun
- Appetite suppression
Common Uses
What to Expect
Onset
Tanning visible within 2–5 days; libido effects can occur within hours of the first dose
Duration
Tan lasts weeks with maintenance dosing; libido effects last 6–12 hours per dose
What Users Report
- Noticeable tanning even with minimal sun exposure — skin darkens progressively over the loading phase
- Nausea after injection is common, especially in the first few doses; starting low (0.25 mg) helps
- Facial flushing and warmth for 30–60 minutes post-injection
- Significant increase in libido, particularly in men — sometimes unexpectedly strong
- Darkening of existing moles, freckles, and birthmarks (important to monitor)
- Appetite suppression — many find they eat less without trying
- Spontaneous erections in men can occur, especially during the loading phase
- Stomach discomfort and nausea improve significantly after the first 3–5 injections
Typical Timeline
Hours 0–1: Flushing, possible nausea, libido effects begin. Days 2–5: Tanning becomes visible, especially with some UV exposure. Days 5–10: Loading phase complete; desired tan level typically reached. Maintenance: 1–2 injections per week maintain the tan with minimal side effects. Note: Monitor moles throughout use.
Side Effects
- Nausea
- Facial flushing
Dosage Protocol
Loading: 0.25–1 mg subcutaneously daily until tan. Maintenance: 0.25–0.5 mg 1–2x/week.
Always consult a physician before starting any peptide protocol.
Administration
Injection
FDA Status
Category 2 (potential reclassification 2026)